Tag: Antibodies
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Tacrolimus
Brands Classes DEA Class; Rx Common Brand Names; Prograf, Astagraf XL, Hecoria, Envarsus XR, Protopic Immunosuppressants; Calcineurin Inhibitors Description Immunosuppressant; more potent than cyclosporine Used for graft rejection prophylaxis and treatment of acute or refractory graft rejection; considered an alternative to cyclosporine; topical formulation used for atopic dermatitisIncreased susceptibility to infections and secondary malignancy possible Indications Indicated…
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Cyclosporine
Brands Classes DEA Class; Rx Common Brand Names; Neoral, Sandimmune, Gengraf DMARDs, Immunomodulators; Immunosuppressants; Calcineurin Inhibitors Description Immunosuppressive; cyclic polypeptide consisting of 11 amino acidsUsed to prevent organ rejection and in various autoimmune conditions; ophthalmic 0.05% emulsion and 0.09% solution used to increase tear production in patients with ocular inflammation associated with keratoconjunctivitis; 0.1% ophthalmic…
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Basiliximab
Brands Classes DEA Class; Rx Common Brand Names; Simulect Immunouppressants; Monoclonal Antibodies Description Immunosuppressant; chimeric (murine/human) monoclonal antibody (IgG); binds to and blocks the interleukin-2 receptor alpha chain (CD25); has not been associated with an increased risk of lymphoma or other malignancies. Indications Indicated for acute kidney transplant rejection prophylaxis when used as part of…
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Antithymocyte Globulin
Brands Classes DEA Class; Rx Common Brand Names; Atgam, ATG equine Immunosuppressants; Polyclonal Antibodies Description Immunosuppressant, polyclonal IgG against human T-lymphocytes derived from horses (Atgam) or rabbits (Thymoglobulin)Used for kidney organ transplant rejection, organ transplant rejection prophylaxis, and moderate to severe aplastic anemiaRisk of serious hypersensitivity reactions, including anaphylaxis or cytokine release syndrome (CRS) Indications…