DrugsAce

Tag: Antibiotics

  • Mitoxantrone

    Brands Classes DEA Class; Rx Common Brand Names; Novantrone Antineoplastics, Anthracenedione;  Multiple Sclerosis Treatments Description Anthracenedione; structurally similar to the anthracyclines; causes less cardiotoxicity than anthracylines; not a vesicant; used in hematologic malignancies and prostate cancer; also effective in relapsing-remitting and secondary progressive MS. Indications Indicated for the treatment of acute myelogenous leukemia (AML). For…

  • Idarubicin

    Brands Classes DEA Class; Rx Common Brand Names; Idamycin Antineoplastics, Anthracycline Description Anthracycline chemotherapy agentUsed in combination with other antileukemia drugs in adults with acute myelogenous leukemiaCardiotoxicity and myelosuppression have been reported Indications Indicated for the treatment of acute myelogenous leukemia (AML). For the treatment of acute promyelocytic leukemia (APL).For the treatment of acute lymphocytic…

  • Epirubicin

    Brands Classes DEA Class; Rx Common Brand Names; Ellence Antineoplastics, Anthracycline Description Anthracycline topoisomerase inhibitorUsed for node-positive early breast cancerContraindicated in patients with severe drug-induced myelosuppression, severe myocardial insufficiency, recent myocardial infarction, severe arrhythmias, and severe hepatic impairment Indications Indicated as a component of adjuvant therapy in patient with evidence of axillary node tumor involvement…

  • Doxorubicin

    Brands Classes DEA Class; Rx Common Brand Names; Adriamycin, Caelyx, Rubex, Doxil, Lipodox, Myocet Antineoplastics, Anthracycline Description A cytotoxic anthracycline antibiotic that inhibits nucleotide replication and repairApproved for use in certain types of leukemias, lymphomas, and solid tumorsCardiotoxicity including congestive heart failure has been reported; use is contraindicated in patients with severe myocardial insufficiency or recent myocardial…

  • Daunorubicin

    Brands Classes DEA Class; Rx Common Brand Names; Cerubidine Antineoplastics, Anthracycline Description Anthracycline chemotherapy agentUsed in combination with other anticancer drugs in patients with acute leukemiasCardiotoxicity and myelosuppression have been reported Indications Indicated for the treatment of acute nonlymphocytic leukemia including acute myelogenous leukemia (AML). For the treatment of acute lymphocytic leukemia (ALL). Contraindications Hypersensitivity…

  • Bleomycin

    Brands Classes DEA Class; Rx Common Brand Names; Blenoxane Antineoplastics, Antibiotic Description Antibiotic antineoplasticMixture of 13 glycopeptides; active component is the A-2 peptideUsed for Hodgkin lymphoma, NHL, testicular cancer, squamous cell cancer of the head and neck and cervix, and malignant pleural effusions. Indications Indicated for the treatment of Hodgkin lymphoma. For the treatment of…

  • Rifampicin

    Brands Classes DEA Class; Rx Common Brand Names; Rifadin, Rimactane Antitubercular Agents Description Semisynthetic rifamycin antibioticPrimarily used as part of first-line, combination therapy for the treatment of tuberculosis and also used to treat asymptomatic carriers of Neisseria meningitidisPotent inducer of hepatic microsomal enzymes and associated with many significant drug interactions Indications Indicated for Tuberculosis.Indicated for…

  • Dapsone

    Brands Classes DEA Class; Rx Common Brand Names; Aczone Antileprosy Agents,  Acne Agents, Topical Description Synthetic sulfone chemically similar to sulfonamidesHas antiinfective and immunosuppressive propertiesAgent of choice for all forms of leprosy; used for PCP prophylaxis; used in combination with pyrimethamine for prevention of toxoplasmosis in AIDS patients; used for various dermatologic disorders and topically…

  • Clofazimine

    Brands Classes DEA Class; Rx Common Brand Names; Lamprene Antitubercular Agents Description Exerts a slow bactericidal effect on Mycobacterium leprae (Hansen’s bacillus); inhibits mycobacterial growth and binds preferentially to mycobacterial DNA Also exerts anti-inflammatory properties in controlling erythema nodosum leprosum reactions; however, its precise mechanisms of action are unknown Indications Indicated for treatment of lepromatous…

  • Ethionamide

    Brands Classes DEA Class; Rx Common Brand Names; Trecator Antitubercular Agents Description Second-line agent for tuberculosis; for disease resistant to rifampin and/or isoniazid, or for patients who are intolerant of rifampin and isoniazid; used in combination with at least one other antitubercular drug; only film-coated tablets (Trecator®) available. Indications Indicated for the treatment of drug-susceptible…

  • Cycloserine

    Brands Classes DEA Class; Rx Common Brand Names; Capastat Antitubercular Agents Description Bacteriostatic or bactericidal Inhibits cell wall synthesis Indications Indicated for treatment of Tuberculosis Contraindications Hypersensitivity Alcohol use Renal dysfunction, severe History of seizure disorder, mental depression, severe anxiety or psychosis Adverse Effects Confusion Restlessness Drowsiness Vertigo Cardiac arrhythmia Folate deficiency Hyperreflexia Dysarthria Dizziness…

  • Capreomycin

    Brands Classes DEA Class; Rx Common Brand Names; Capastat Antitubercular Agents Description Parenteral polypeptide antibiotic, exact mechanism unknown.Used as a second line agent in combination with other medications for the treatment of pulmonary tuberculosis.Practical use is limited by routes of administration, adverse effects of nephrotoxicity and neurotoxicity. Indications Indicated for treatment of Tuberculosis Contraindications Hypersensitivity…

  • Aminosalicylic Acid

    Brands Classes DEA Class; Rx Common Brand Names; Paser 5-Aminosalicylic Acid Derivatives;  Antitubercular Agents Description Oral antituberculosis agent that may inhibit folic acid synthesis and/or inhibit synthesis of a cell wall component Use second-line to treat tuberculosis infection; often used for multi-drug resistant tuberculosisMust be used as part of a multi-drug treatment regimen Indications Indicated for…

  • Bedaquiline

    Brands Classes DEA Class; Rx Common Brand Names; Sirturo Antitubercular Agents Description Diarylquinoline antimycobacterialFor use in combination with other drugs to treat adults and pediatric patients 5 years and older weighing at least 15 kg with pulmonary multi-drug resistant tuberculosis (MDR-TB) for which no other effective treatment regimens are availableAssociated with an increased risk of…

  • Rifapentine

    Brands Classes DEA Class; Rx Common Brand Names; Priftin Antitubercular Agents Description Oral cyclopentyl rifamycin antimycobacterial drugUsed for treatment of active pulmonary tuberculosis (TB) in combination with 1 or more anti-TB drugs and treatment of latent TB infection in patients at high risk of progression to TB diseaseHepatotoxicity and drug-drug interactions may limit use Indications…