DrugsAce

Tag: Antiarrhythmic Drugs

  • Ranolazine

    Brands Classes DEA Class; Rx Common Brand Names; Ranexa, Aspruzyo Sprinkle Antianginal, Non-nitrates Description Oral antianginal, piperazine derivativeUsed for chronic angina in adultsContraindicated in patients with liver cirrhosis or taking CYP3A inducers or strong CYP3A inhibitors; ranolazine causes dose-related QT prolongation Indications Indicated for the treatment of chronic angina. For the treatment of acute coronary…

  • Magnesium Sulfate

    Brands Classes DEA Class; Rx Common Brand Names; MgSO4 Antidysrhythmics, V;  Electrolytes Description Depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects; decreases amount of acetylcholine released at end-plate by motor nerve impulse Slows rate of SA node impulse formation in myocardium and prolongs conduction time Promotes movement of calcium, potassium, and sodium in and…

  • Adenosine

    Brands Classes DEA Class; Rx Common Brand Names; Adenocard, Adenoscan Antidysrhythmics, V Description Parenteral pharmacologic stress agent and antiarrhythmicUsed for adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately and for conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT)Associated with cardiac arrest, sustained ventricular tachycardia, myocardial infarction, bronchoconstriction, and respiratory compromise;…

  • Sotalol

    Brands Classes DEA Class; Rx Common Brand Names; Betapace, Betapace AF, Sorine, Sotylize Antidysrhythmics, II;  Antidysrhythmics, III;  Beta-Blockers, Nonselective Description Nonselective beta-adrenergic blocking agent and class III antiarrhythmicUsed for the treatment of atrial fibrillation, atrial flutter, and life-threatening ventricular arrhythmiasMay induce QT prolongation and torsade de pointes Indications Indicated for treatment of life-threatening ventricular tachycardia; antiarrhythmic…

  • Ibutilide

    Brands Classes DEA Class; Rx Common Brand Names; Corvert Antidysrhythmics, III Description Class III antiarrhythmic agent; used IV for rapid conversion of atrial fibrillation or atrial flutter to normal sinus rhythm. Indications Indicated for the rapid cardioversion of recent onset atrial fibrillation or atrial flutter. Contraindications Hypersensitivity to drug or excipients Adverse Effects Headache (4%)…

  • Dofetilide

    Brands Classes DEA Class; Rx Common Brand Names; Tikosyn Antidysrhythmics, III Description Class III antiarrhythmic; converts and maintains NSR in AFIB/Flutter; reserved for highly symptomatic patients; proarrhythmic (torsade de pointes); selectively blocks potassium channels; prolongs QT, APD, and ERP; does not affect ventricular conduction time; has negative chronotropy; lacks negative inotropy; renally eliminated; numerous drug…

  • Dronedarone

    Brands Classes DEA Class; Rx Common Brand Names; Multaq Antidysrhythmics, III Description Antiarrhythmic agent similar in efficacy to amiodaroneUsed to reduce hospitalization risk for AF in patients in sinus rhythm with history of paroxysmal or persistent AFContraindicated in certain patients with heart failure or permanent AF Indications Indicated for reduction in the risk of hospitalization…

  • Amiodarone

    Brands Classes DEA Class; Rx Common Brand Names; Pacerone, Cordarone, Nexterone Antidysrhythmics, III Description Class III antiarrhythmic agentUsed for ventricular and supraventricular tachyarrhythmiasRisk of proarrhythmias less than other antiarrhythmics Indications Indicated for the treatment of life-threatening recurrent ventricular fibrillation or hemodynamically unstable (symptomatic) sustained ventricular tachycardia, including post-myocardial infarction (MI) patients. For the treatment of atrial…

  • Dextromethorphan/Quinidine

    Brands Classes DEA Class; Rx Common Brand Names; Nuedexta NMDA Antagonists Description Oral combination of dextromethorphan and low-dose quinidine.Used for pseudobulbar affect (PBA); quinidine, a 2D6 inhibitor, increases the bioavailability of dextromethorphan, the active entity.Due to the potential for quinidine to cause QT prolongation, contraindications apply to patients with certain cardiac conditions or those receiving…

  • Quinidine

    Brands Classes DEA Class; Rx Common Brand Names; Quinaglute, Quinidex, quinidine gluconate Antidysrhythmics, Ia;  Antimalarials Description Parenteral and oral class IA antiarrhythmic; used for atrial arrhythmias and ventricular tachycardia; also used for severe malaria. Indications Indicated for conversion to and/or maintenance of sinus rhythm in patients with atrial fibrillation, atrial flutter, or ventricular tachycardia; or for…

  • Propafenone

    Brands Classes DEA Class; Rx Common Brand Names; Rythmol, Rythmol SR Antidysrhythmics, Ic Description Oral class IC antiarrhythmic; used to suppress life-threatening ventricular arrhythmias; mechanism similar to encainide and flecainide; possesses beta-blocking activity; proarrhythmic; should be initiated in the hospital to allow for appropriate ECG monitoring. Indications Indicated for the treatment of sustained ventricular tachycardia…

  • Procainamide

    Brands Classes DEA Class; Rx Common Brand Names; Pronestyl (SR) Antidysrhythmics, Ia Description IV class IA antiarrhythmic agentUsed for atrial fibrillation/flutter, paroxysmal atrial tachycardia, and ventricular tachycardiaDerivative of the local anesthetic procaine Indications Indicated for the treatment of ventricular tachycardia with pulses (stable monomorphic or wide-complex regular ventricular tachycardia) during cardiopulmonary resuscitation (CPR) in patients…

  • Mexiletine

    Brands Classes DEA Class; Rx Common Brand Names; Tambocor Antidysrhythmics, Ib Description Oral, Class IB, local anesthetic-type antiarrhythmic; similar to lidocaine and tocainide; used to treat life-threatening ventricular arrhythmias; associated with proarrhythmic effects; also used successfully to treat neuropathic pain due to diabetic neuropathy. Indications Indicated Oral, Class IB, local anesthetic-type antiarrhythmic; similar to lidocaine…

  • Flecainide

    Brands Classes DEA Class; Rx Common Brand Names; Tambocor Antidysrhythmics, Ic Description Oral Class IC antiarrhythmic; used to treat documented life-threatening ventricular arrhythmias; should be avoided in LVD or asymptomatic post-MI patients; also approved for prevention of PSVT; not considered first-line agent for suppression of ventricular arrhythmias due to risk of proarrhythmias (CAST trial). Indications…

  • Disopyramide

    Brands Classes DEA Class; Rx Common Brand Names; Norpace, Norpace CR Antidysrhythmics, Ia Description Oral class IA antiarrhythmic; similar pharmacology to procainamide and quinidineUsed only for life-threatening ventricular arrhythmiaSignificant proarrhythmic, anticholinergic, and negative inotropic properties limit its use Indications Indicated for the treatment of documented, life-threatening arrhythmias such as sustained ventricular tachycardia.For maintenance of sinus…