Tag: ACE Inhibitors

  • Trandolapril/Verapamil

    Brands Classes DEA Class; Rx Common Brand Names; Tarka ACE Inhibitors Description ACE inhibitor and CCB; used qd for HTN; oral combination product contains immediate-release trandolapril and extended-release verapamil; has greater antihypertensive effects than either agent alone. Indications Indicated for the treatment of hypertension. Not indicated for initial therapy For the treatment of hypertension in…

  • Trandolapril

    Brands Classes DEA Class; Rx Common Brand Names; Mavik ACE Inhibitors Description Oral ACE inhibitor; structurally similar to enalapril, requiring hydrolysis for activity; used once daily for HTN and to reduce cardiovascular morbidity and mortality following AMI. Indications Indicated for the treatment of hypertension. For the treatment of heart failure postmyocardial infarction or left-ventricular dysfunction…

  • Ramipril

    Brands Classes DEA Class; Rx Common Brand Names; Altace ACE Inhibitors Description ACE inhibitor; prodrug metabolized to active ramiprilat; used 1—2 times daily for HTN; also used to reduce proteinuria and slow the progression of renal disease from various nephropathies; given twice daily for CHF, AMI, and post-MI. Indications Indicated for reduction of cardiovascular mortality,…

  • Perindopril/​Amlodipine

    Brands Classes DEA Class; Rx Common Brand Names; Prestalia ACEI/CCB Combos Description Combination dihydropyridine calcium-channel blocker (amlodipine) and ACE inhibitor (perindopril)Used for hypertensionBlack box warning for use during pregnancy Indications Indicated for the treatment of hypertension in patients likely to need multiple drugs to achieve their blood pressure goals or in patients not adequately controlled…

  • Perindopril

    Brands Classes DEA Class; Rx Common Brand Names; Aceon ACE Inhibitors Description Angiotensin converting enzyme (ACE) inhibitors dilate arteries and veins by competitively inhibiting the conversion of angiotensin I to angiotensin II (a potent endogenous vasoconstrictor) and by inhibiting bradykinin metabolism; these actions result in preload and afterload reductions on the heart ACE inhibitors also…

  • Quinapril

    Brands Classes DEA Class; Rx Common Brand Names; Accupril ACE Inhibitors Description Oral ACE inhibitor; prodrug metabolized to active quinaprilat; used 1-2 times daily for HTN; given twice daily for CHF. Indications Indicated for the treatment of hypertension For the treatment of heart failure.For the treatment of diabetic cardiovascular autonomic neuropathy. Contraindications Hypersensitivity History of…

  • Moexipril

    Brands Classes DEA Class; Rx Common Brand Names; Univasc ACE Inhibitors Description Angiotensin converting enzyme (ACE) inhibitors dilate arteries and veins by competitively inhibiting the conversion of angiotensin I to angiotensin II (a potent endogenous vasoconstrictor) and by inhibiting bradykinin metabolism; these actions result in preload and afterload reductions on the heart ACE inhibitors also…

  • Lisinopril

    Brands Classes DEA Class; Rx Common Brand Names; Prinivil, Zestril, Qbrelis ACE Inhibitors Description Long-acting, oral ACE inhibitorUsed for hypertension, congestive heart failure, post-myocardial infarction, and diabetic nephropathyCan be dosed once daily; slower onset and a longer duration of action than either captopril or enalapril Indications Indicated for the treatment of hypertension For the treatment of…

  • Fosinopril

    Brands Classes DEA Class; Rx Common Brand Names; Monopril ACE Inhibitors Description Oral ACE inhibitor; prodrug metabolized to active fosinoprilat; used once daily or in divided doses for both HTN and CHF; also has been used post-MI, but not FDA-approved; does not require dosage adjustment in renal failure, hepatic impairment, or dialysis. Indications Indicated for…

  • Enalapril

    Brands Classes DEA Class; Rx Common Brand Names; enalaprilat, Epaned, Vasotec, Vasotec IV ACE Inhibitors Description IV and oral ACE inhibitor; used for hypertension and CHF; longer-acting than captopril but shorter-acting than other ACE inhibitors; usually dosed twice daily when given orally. Indications Indicated for the treatment of hypertension For the treatment of heart failure.For the…

  • Captopril

    Brands Classes DEA Class; Rx Common Brand Names; Capoten, Captoril ACE Inhibitors Description Shortest acting, oral ACE inhibitor; contains a sulfhydryl group; side effects increase at higher doses; may be used for HTN, CHF, and various renal syndromes (e.g., diabetic nephropathy, proteinuria, scleroderma renal crisis). Indications Indicated for the treatment of hypertension For the treatment…

  • Benazepril/Amlodipine

    Brands Classes DEA Class; Rx Common Brand Names; Lotrel Antihypertensive Combos, Other;  ACEI/CCB Combos;  Calcium Channel Blockers, Dihydropyridine Description Oral combination product containing a dihydropyridine calcium-channel blocker (amlodipine) and an angiotensin-converting enzyme (ACE) inhibitor (benazepril)Used for hypertension in adultsUsed after titration of individual medication components Indications Indicated for the treatment of hypertension in patients who…

  • Benazepril

    Brands Classes DEA Class; Rx Common Brand Names; Lotensin ACE Inhibitors Description Direct renin inhibitorUsed for hypertensionBlack box warning for pregnancy Indications Indicated ACE inhibitorUsed for hypertension and congestive heart failureLong duration of action allows for once daily dosing Contraindications Hypersensitivity History of hereditary or idiopathic angioedema Coadministration of neprilysin inhibitors (eg, sacubitril) with ACE…