Classes
DEA Class; Rx
Common Brand Names; Zioptan
- Antiglaucoma, Prostaglandin Agonists
Description
Prostaglandin analog
Used for reducing elevated IOP in patients with open-angle glaucoma or ocular hypertension
May increase pigmentation of eyelashes, iris, and/or eyelid skin
Indications
Indicated for the reduction of increased intraocular pressure in patients with open-angle glaucoma or ocular hypertension..
Adverse Effects
- Conjunctival hyperemia (4-20%)
- Ocular stinging (7%)
- Ocular pruritus/allergic conjunctivitis (5%)
- Cataract (3%)
- Growth of eyelashes (2%)
- Blurred vision (2%)
Warnings
Causes changes to pigmented tissues; most frequently reported changes have been of the iris, eyelid, and eyelashes; pigmentation changes of the iris is likely permanent Increases length, color, thickness, and number of eyelashes
Caution with active intraocular inflammation (may exacerbate condition)
Macular edema reported; caution in aphakic patients, in pseudophakic patients with a torn posterior lens capsule, or with known risk factors for macular edema
Pregnancy and Lactation
Pregnancy Category: C; teratogenic when administered IV in rats and rabbits
Lactation: Unknown whether distributed in breast milk
Maximum Dosage
1 drop/day in each affected eye.
1 drop/day in each affected eye.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
Safety and efficacy have not been established.
Safety and efficacy have not been established.