Oxazepam

DEA Class;  Rx

Common Brand Names; Serax

Documented hypersensitivity

• Sedation
• Ataxia
• Confusion
• Memory impairment
• Dizziness
• Drowsiness
• Muscle weakness
• Syncope edema
• Leukopenia, blood dyscrasias
• Decreased libido
• Rash
• Incontinence
• Menstrual irregularities
• Jaundice
• Blured vision; diplopia

Use caution in respiratory diseases (COPD), sleep apnea, depression, suicide ideation, history of drug abuse

Continued use of benzodiazepines may lead to clinically significant physical dependence; longer treatment duration and higher daily dose increases risk of dependence and withdrawal symptoms; rapid dose reduction or abrupt discontinuation after continued use may result in withdrawal reactions that can be life threatening; to reduce risk of withdrawal reactions gradual taper recommended when discontinuing drug or reducing dosage

Use caution in patients with hepatic impairment, depression, respiratory disease, and debilitated and elderly patients at risk of falls and traumatic injuries

Not for use as analgesic, antipsychotic, or antidepressant

Patients should be warned that the effects of alcohol or other depressant drugs may be additive to those of oxazepam, which may require adjusting dosage or elimination of such patients

Anterograde amnesia reported with benzodiazepines

Sleep-related hazardous activities, including sleep-driving, making phone calls, cooking, and eating food reported with benzodiazepines

Hypotension reported; use caution in patients with cardiovascular or cerebrovascular disease or patients who do not tolerate transient decreases in blood pressure

Paradoxical reactions, including aggressive and hyperactive behavior reported with benzodiazepines, especially in pediatric/adolescent or psychiatric patients

Pregnancy Category: D

Lactation: Avoid during breastfeeding