Nisoldipine

DEA Class; Rx

Common Brand Names; Sular

• Calcium Channel Blockers; 
• Calcium Channel Blockers, Dihydropyridine
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Indicated for the treatment of hypertension.

Hypersensitivity to nisoldipine or other calcium channel blockers

• Peripheral edema (22%)
• Dizziness (5%)
• Palpitation (3%)
• Vasodilation (4%)
• Increased severity of angina (1.5%)
• Nausea (2%)
• Pharyngitis (5%)
• Sinusitis (3%)
• Gingival hyperplasia
• Colitis
• Anemia
• Alopecia
• Anorexia
• Anxiety
• Ischemia
• Diabetes mellitus
• Dyspepsia
• Dysphagia

Use caution in CHF, aortic stenosis, hypotension (initially or after dose increases), persistent progressive dermatologic reactions, exacerbation of angina (during initiation of treatment, after dose increased, beta blocker withdrawal), liver impairment

Reflex tachycardia resulting in angina and/or MI in patients with obstructive coronary disease reported

Peripheral edema may occur within 2-3 weeks of initiating therapy

Hypotension with or without syncope is possible (particularly with severe aortic stenosis)

Do not take with high fat meal or grapefruit products

Start at lower dose with liver/kidney dysfunction, elderly

Pregnancy Category: C

Lactation: not known if excreted in breast milk, use caution