Classes
DEA Class; Rx
Common Brand Names; Corlopam
- Vasodilators;
- Endocrine, Dopamine Agonists
Description
Intravenous dopamine1 agonist
Used for in-hospital, short-term (up to 48 hours) treatment of severe hypertension
Transition to oral therapy after blood pressure stable during fenoldopam infusion
Indications
Contraindications
Hypersensitivity to fenoldopam and sulfite
Adverse Effects
- Angina
- Cardiac dysrhythmia
- Dizziness
- Flushing
- Heart failure
- Hypotension
- Myocardial infarction
- Tachycardia
- Headache
- Nausea
- Vomiting
- Serum creatinine raised
- Cardiac disorders: Cardiogenic shock
- Gastrointestinal disorders: Abdominal distension
Warnings
Causes a dose-related tachycardia, particularly with infusion rates above 0.1 mcg/kg/min
Monitor potassium levels
Increased intraocular pressure in patients with glaucoma or intraocular hypertension
Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms in susceptible patients
Pregnancy and Lactation
There are insufficient data regarding use in pregnancy to evaluate for a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes
There are no data on presence of drug in human milk, effects on breastfed child, or on milk production; drug is present in rat milk; when a drug is present in animal milk, it is likely that the drug will be present in human milk
Maximum Dosage
1.6 mcg/kg/minute IV.
1.6 mcg/kg/minute IV.
0.8 mcg/kg/minute IV.
0.8 mcg/kg/minute IV.
0.8 mcg/kg/minute IV.
Weighing 2 kg or more: 0.8 mcg/kg/minute IV.
How supplied
Fenoldopam mesylate
injectable solution
- 10mg/mL