DrugsAce

Category: Drugs Generic

  • Diethylcarbamazine

    Brands Classes DEA Class; Rx Common Brand Names; Hetrazan Anthelmintics Description Microfilaricidal and macrofilaricidal Indications Indicated for Filarial Diseases Loa Loa M. Streptocerca Tropical Pulmonary Eosinophilia  Larva Migrans, Visceral Contraindications No studies reported Adverse Effects Encepholopathy (rare) Fever GI disturbances Warnings — Pregnancy and Lactation Pregnancy Category: X Lactation: not known if excreted in breast milk…

  • Nitazoxanide

    Brands Classes DEA Class; Rx Common Brand Names; Alinia Antiparasitic Agents Description Oral synthetic antiprotozoal agent for treatment of cryptosporidiosis or giardiasis caused by Cryptosporidium parvum or Giardia lamblia, respectively; is the first drug specifically approved for treating cryptosporidiosis; also effective in treating diarrhea due to other protozoa such as Giardia duodenalis, G. intestinalis and Entamoeba…

  • Sodium Stibogluconate

    Brands Classes DEA Class; Rx Common Brand Names; Pentostam, stibogluconate sodium Antileishmaniasis Agents Description Reduction in the fructose diphosphate and an inhibition of glycolysis Indications Indicated for the treatment of Leishmaniasis (Orphan) Orphan designation for treatment of acute myeloid leukemia (AML) Contraindications Hypersensitivity Significant renal impairment; breast-feeding Adverse Effects Anorexia Nausea/vomiting Abdominal pain ECG changes Headache…

  • Miltefosine

    Brands Classes DEA Class; Rx Common Brand Names; Impavido Antileishmaniasis Agents Description Oral anti-leishmanial agentUsed for the treatment of visceral, cutaneous, and mucosal leishmaniasis in adults and pediatric patients 12 years of age and older and weighing at least 30 kgContraindicated during pregnancy; may impair male fertility Indications Indicated for the treatment of leishmaniasis. Visceral leishmaniasis…

  • Suramin

    Brands Classes DEA Class; Rx Common Brand Names; Suramin sodium Antiprotozoal Agents Description Trypanocidal activity; inhibits enzymes involved with the oxidation of reduced NADH Indications Indicated for  Trypanosomiasis TB Gambiense Treatment of hormone-refractory prostate cancer Contraindications Hypersensitivity Adverse Effects Vomiting Urticaria Paresthesia Peripheral neuropathy Kidney damage Blood dyscrasias Polyuria Polydipsia Pancytopenia Shock Optic atrophy Warnings Proteinuria…

  • Pentamidine

    Brands Classes DEA Class; Rx Common Brand Names; NebuPent, Pentam Antipneumocystis Agents Description Oral inhalation/IM/IV antifungal agentUsed for Pneumocystis jiroveci (Pneumocystis carinii) pneumonia treatment and prophylaxis Parenteral administration is associated with several major ADRs Indications Indicated for the treatment of Pneumocystis pneumonia (PCP).For pneumocystis pneumonia (PCP) prophylaxis.For the treatment of leishmaniasis.For the treatment of African trypanosomiasis (sleeping…

  • Nifurtimox

    Brands Classes DEA Class; Rx Common Brand Names; Lampit Antiprotozoal Agents Description Antiprotozoal agent Mechanism of action is not fully understood May react with the nucleic acids of the parasite and inhibits trypanothione reductase, a parasite-specific antioxidant defense enzyme Indications Orphan designation for Chagas Disease (American Trypanosomiasis) Contraindications Hypersensitivity to nifurtimox or any of the excipients…

  • Melarsoprol

    Brands Classes DEA Class; Rx Common Brand Names; Arsobal Antiprotozoal Agents Description Inhibits synthesis of ATP – the energy required for survival of the parasite Indications Indicated for the African Trypanosomiasis (Sleeping Sickness) Contraindications Glucose-6-phosphate dehydrogenase (G6PD) deficiency, hypersensitivity Adverse Effects Hypertension Myocardial damage Encephalopathy Peripheral neuropathy Colic Vomiting Albuminuria Herxheimer-type reaction Warnings — Pregnancy and…

  • Eflornithine

    Brands Classes DEA Class; Rx Common Brand Names; Ornidyl, Vaniqa Antiprotozoal Agents Topical Skin Products Description Antiprotozoal agentUsed topically to reduce unwanted facial hair in women and parenterally to treat African trypanosomiasis (sleeping sickness)In US only available as topical cream; IV only available from the WHO/CDC Indications Indicated for the reduction of unwanted facial hair in…

  • Benznidazole

    Brands Classes DEA Class; Rx Common Brand Names; Benznidazole Antiparasitic Agents Description AntiprotozoalUsed for the treatment of Chagas disease or American trypanosomiasis, a parasitic infection caused by Trypanosoma cruziOnly approved for pediatric patients 2 to 12 years, although used off-label in patients of all ages Indications Indicated for the treatment of American trypanosomiasis (Chagas disease). Contraindications…

  • Quinine

    Brands Classes DEA Class; Rx Common Brand Names; Qualaquin Antimalarials;  Description Antimalarial; occurs naturally in the bark of the cinchona tree; more toxic and potent antimalarial than quinidine; FDA ruled that it lacked evidence of effectiveness for relief of nocturnal muscle cramps; non-prescription forms are no longer available but prescription forms are still available. Indications Indicated…

  • Primaquine

    Brands Classes DEA Class; Rx Common Brand Names; Primaquine Antimalarials;  Antimalarials, Aminoquinoline Description Oral antimalarial agent; chemically related to chloroquine; not effective against asexual erythrocytic forms; alternative agent for PCP in combination with clindamycin. Indications Indicated for the radical cure (prevention of relapse) of malaria due to P. vivax or P. ovale in patients who are receiving appropriate antimalarial…

  • Mefloquine

    Brands Classes DEA Class; Rx Common Brand Names; Lariam Antimalarials Description Oral antimalarial agent used for malaria prophylaxis or treatment. Prophylactic dosing should begin 1 week before entering endemic area and continue for 4 weeks after leaving. Alternative antimalarial in areas where chloroquine- and proguanil-resistant strains of malaria exist (i.e., European countries). Treatment of choice for…

  • Atovaquone/Proguanil

    Brands Classes DEA Class; Rx Common Brand Names; Malarone Antimalarials Description Oral antimalarial combination with potent synergistic antimalarial activity. Atovaquone is structurally and pharmacologically related to the older antimalarials, lapinone and parvaquone. Proguanil is a synthetic biguanide derivative of pyrimidine and a prodrug for cycloguanil. Certain populations are poor metabolizers (e.g., Asian and African populations) of…

  • Atovaquone

    Brands Classes DEA Class; Rx Common Brand Names; Mepron Antimalarials Description Oral antiprotozoal agent; active against both Toxoplasma gondii and Pneumocystis jiroveci (formerly Pneumocystis carinii); structurally and pharmacologically related to lapinone and parvaquone (antimalarials); effective for malaria when used with proguanil. Indications Indicated for the treatment Pneumocystis Carinii Pneumonia Malaria (P. falciparum) Contraindications History of hypersensitivity…