DrugsAce

Category: Drugs Generic

  • Azelastine/Fluticasone

    Brands Classes DEA Class; Rx Common Brand Names; Dymista Allergy, Intranasal;  Corticosteroids, Intranasal Description Nasal combination of an H1-blocker antihistamine (azelastine) and a corticosteroid (fluticasone)Used to treat seasonal allergic rhinitis in adult and pediatric patients 6 years and olderCombination primarily used for patients not responding to monotherapy, or those with initial severe symptoms Indications Indicated…

  • Azelastine

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Astelin Nasal Spray, Astepro, Astepro Allergy, Children’s Astepro Allergy Allergy, Intranasal;  Antihistamines, Intranasal azelastine ophthalmic (Rx) Brand and Other Names:Optivar Classes: Antihistamines, Ophthalmic   Description Second-generation nasal and ophthalmic antihistamine (H1-blocker)Used nasally for allergic or vasomotor rhinitis and as an ophthalmic solution for itching related to allergic conjunctivitisDrowsiness rates…

  • Alcaftadine

    Brands Classes DEA Class; OTC Common Brand Names; Lastacaft  Antihistamines, Ophthalmic   Description Topical ophthalmic H1-antagonistUsed for the prevention of ocular pruritus associated with allergic conjunctivitisOnce daily administration Indications Indicated for prevention of itching associated with allergic conjunctivitis Contraindications Hypersensitivity Adverse Effects Ocular Irritation Burning Stinging Redness Pruritus Eye discharge Eye swelling Erythema of eyelid…

  • Mycophenolate

    Brands Classes DEA Class; Rx Common Brand Names; CellCept, Myfortic, MMF Immunosuppressants   Description Immunosuppressant with mycophenolic acid (MPA) as active component; similar efficacy with mofetil or sodium formulasUsed for organ rejection prophylaxis in conjunction with other immunosuppressants, in adult and pediatric patients 3 months and olderMay increase the risk of fetal harm (birth defects) and…

  • Sirolimus

    Brands Classes DEA Class; Rx Common Brand Names; Rapamune Immunosuppressants sirolimus topical (Rx) Brand and Other Names: Hyftor Classes: Dermatologics, mTOR Inhibitors sirolimus protein bound (Rx) Brand and Other Names: Fyarro Classes: Antineoplastics, mTOr Kinase Inhibitor   Description Immunosuppressant; analog of tacrolimusOral formulations for prophylaxis of organ rejection in renal transplant patients and for lymphangioleiomyomatosis; topical gel for facial…

  • Everolimus

    Brands Classes DEA Class; Rx Common Brand Names; Afinitor, Zortress, Afinitor Disperz Antineoplastics, mTOr Kinase Inhibitors Description Macrolide immunosuppressant analog of sirolimus; inhibits the mammalian target of rapamycin (mTOR), a serine-threonine kinaseAfinitor is used for certain patients with breast cancer, neuroendocrine tumors of pancreatic, GI, or lung origin, renal cell carcinoma, and certain tuberous sclerosis complex…

  • Belatacept

    Brands Classes DEA Class; Rx Common Brand Names; Nulojix Immunosuppressants;  Selective T-Cell Costimulation Blockers Description Selective T-cell costimulation blockerFor rejection prophylaxis in adults receiving a kidney transplantMay increase risk for developing post-transplant lymphoproliferative disorder; ONLY use in Epstein-Barr virus seropositive patients Indications Indicated for use in combination with basiliximab induction, mycophenolate mofetil, and corticosteroids to…

  • Tacrolimus

    Brands Classes DEA Class; Rx Common Brand Names; Prograf, Astagraf XL, Hecoria, Envarsus XR, Protopic Immunosuppressants;  Calcineurin Inhibitors Description Immunosuppressant; more potent than cyclosporine Used for graft rejection prophylaxis and treatment of acute or refractory graft rejection; considered an alternative to cyclosporine; topical formulation used for atopic dermatitisIncreased susceptibility to infections and secondary malignancy possible Indications Indicated…

  • Cyclosporine

    Brands Classes DEA Class; Rx Common Brand Names; Neoral, Sandimmune, Gengraf DMARDs, Immunomodulators;  Immunosuppressants;  Calcineurin Inhibitors   Description Immunosuppressive; cyclic polypeptide consisting of 11 amino acidsUsed to prevent organ rejection and in various autoimmune conditions; ophthalmic 0.05% emulsion and 0.09% solution used to increase tear production in patients with ocular inflammation associated with keratoconjunctivitis; 0.1% ophthalmic…

  • Basiliximab

    Brands Classes DEA Class; Rx Common Brand Names; Simulect Immunouppressants;  Monoclonal Antibodies Description Immunosuppressant; chimeric (murine/human) monoclonal antibody (IgG); binds to and blocks the interleukin-2 receptor alpha chain (CD25); has not been associated with an increased risk of lymphoma or other malignancies. Indications Indicated for acute kidney transplant rejection prophylaxis when used as part of…

  • Antithymocyte Globulin

    Brands Classes DEA Class; Rx Common Brand Names; Atgam, ATG equine Immunosuppressants;  Polyclonal Antibodies Description Immunosuppressant, polyclonal IgG against human T-lymphocytes derived from horses (Atgam) or rabbits (Thymoglobulin)Used for kidney organ transplant rejection, organ transplant rejection prophylaxis, and moderate to severe aplastic anemiaRisk of serious hypersensitivity reactions, including anaphylaxis or cytokine release syndrome (CRS) Indications…

  • Topotecan

    Brands Classes DEA Class; Rx Common Brand Names; Hycamtin Antineoplastics, Topoisomerase Inhibitors;  Antineoplastics, Camptothecin Description A camptothecin derivative, topoisomerase I inhibitorUsed for the treatment of small cell lung cancer, cervical cancer, and ovarian cancerCan cause severe myelosuppression; closely monitor complete blood counts Indications Indicated for SCLC sensitive disease after failure of first-line chemotherapy Indicated for…

  • Thalidomide

    Brands Classes DEA Class; Rx Common Brand Names; Thalomid Antineoplastics, Angiogenesis Inhibitor Description Biologic response modifier with immunomodulatory, antiangiogenic, and antitumor propertiesUsed for patients with erythema nodosum leprosum; also used in combination with dexamethasone for the treatment of patients with newly diagnosed multiple myelomaKnown teratogen that may cause birth defects or embryo-fetal death; routine testing…

  • Pomalidomide

    Brands Classes DEA Class; Rx Common Brand Names; Pomalyst Antineoplastics, Angiogenesis Inhibitor Description Biologic response modifier that is a thalidomide analogUsed for the treatment of adult patients with multiple myeloma or Kaposi sarcomaRisk of birth defects or embryo-fetal death if used during pregnancy; routine testing required; prescribers, pharmacies Indications Indicated in combination with dexamethasone, for…

  • Pembrolizumab

    Brands Classes DEA Class; Rx Common Brand Names; Keytruda Antineoplastics, Monoclonal Antibody;  PD-1/PD-L1 Inhibitors Description Programmed death receptor-1 (PD-1) blocking human monoclonal antibodyUsed for certain types of lymphoma, skin cancer, solid tumors, and tumors with genomic instability or a high mutational burdenSerious immune-mediated adverse reactions (e.g., pneumonitis, colitis, hepatitis, nephritis/renal dysfunction, hypothyroidism/hyperthyroidism) have been reported…