Category: Drugs Generic

  • Omeprazole/Sodium Bicarbonate

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Zegerid, Zegerid OTC, Konvomep Antacids, Combos;  Proton Pump Inhibitors Description Oral immediate-release proton pump inhibitor (PPI) combined with a sodium bicarbonate bufferPrescription products used for GERD, erosive esophagitis, gastric and duodenal ulcer, and stress ulcer prophylaxis in critically ill patientsNonprescription products used for short-term use (14 days)…

  • Omeprazole

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Prilosec, Prilosec OTC, OmepraCare, OmepraCare DR Proton Pump Inhibitors Description Oral proton pump inhibitor (PPI), gastric antisecretory agent.Used for GERD, erosive esophagitis, and hypersecretory conditions; also used in antimicrobial combination regimens for H. pylori eradication.Available OTC for heartburn. Indications  Indicated for the short-term, self-treatment of frequent dyspepsia…

  • Lansoprazole

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Prevacid, Prevacid Solu Tab, Prevacid 24HR Proton Pump Inhibitors Description Proton-pump inhibitor (PPI), gastric antisecretory agentUsed for treatment of duodenal and gastric ulcers, erosive esophagitis, GERD, heartburn, ZE syndrome, and NSAID-induced ulcers; combined with antibiotics for eradication of H. pyloriAssociated with increased risk of Clostridium difficile-associated diarrhea…

  • Esomeprazole

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Nexium, Nexium 24HR Proton Pump Inhibitors Description Proton pump inhibitor; S-isomer of omeprazoleUsed for GERD, NSAID-induced ulcer healing and prevention, erosive esophagitis, H. pylori eradication, upper GI rebleeding prophylaxis after therapeutic endoscopy, and hypersecretory conditions; available OTC for short-term treatment of heartburnAvoid concomitant use with clopidogrel;…

  • Dexlansoprazole

    Brands Classes DEA Class; Rx Common Brand Names; Dexilant, Kapidex, Dexilant SoluTab Proton Pump Inhibitors Description Proton-pump inhibitor (PPI); R-enantiomer of lansoprazoleUsed for healing and maintenance of erosive esophagitis and treatment of GERDAvailable as a delay-release capsule and disintegrating tablet Indications  Indicated for healing of all grades of erosive esophagitis (EE) and maintaining healing of EE…

  • Ranitidine

    Discontinued Classes DEA Class; Rx Common Brand Names; Zantac, Zantac 150 Maximum Strength, Zantac 75 Histamine H2 Antagonists Description On April 1, 2020, FDA requests removal of all ranitidine products (Zantac) from the market Oral and parenteral histamine type 2-receptor antagonist; ranitidine products withdrawn from U.S. market due to NDMA impurityUsed for gastrointestinal disorders such as…

  • Nizatidine

    Brands Classes DEA Class; Rx Common Brand Names; Axid Histamine H2 Antagonists Description Oral histamine type 2-receptor antagonistUsed for gastroesophageal reflux disease (GERD), short-term and maintenance treatment of duodenal ulcer, and short-term treatment of active benign gastric ulcerFor GERD, proton pump inhibitors (PPIs) are considered to be more effective than H2-blockers Indications Indicated for  Active…

  • Famotidine

    Brands Classes DEA Class; Rx, OTC Common Brand Names; Pepcid AC, Zantac 360 Histamine H2 Antagonists Description Oral/parenteral histamine type 2-receptor antagonistUsed for GI disorders such as peptic ulcer and gastroesophageal reflux diseaseFewer drug interactions than cimetidine Indications Indicated for  Duodenal Ulcer Benign Gastric Ulcer Gastroesophageal Reflux Disease Hypersecretory Conditions Heartburn Contraindications Hypersensitivity to famotidine…

  • Cimetidine

    Brands Classes DEA Class; Rx Common Brand Names; Tagamet HB Histamine H2 Antagonists Description Oral/parenteral histamine type 2-receptor antagonist.Used for gastrointestinal disorders such as peptic ulcer and gastroesophageal reflux disease (GERD)Exhibits many clinically significant drug interactions due to inhibition of CYP450 enzymes. Indications Indicated for  Benign Gastric Ulcer Duodenal Ulcer Erosive Gastroesophageal Reflux Disease Heartburn…

  • Metronidazole/Tetracycline/Bismuth Subsalicylate

    Brands Classes DEA Class; Rx Common Brand Names;  H pylori Agents Description Metronidazole, tetracycline: Inhibits nucleic acid synthesis by disrupting DNA Bismuth Subsalicylate: Antisecretory effect by salicylate, antimicrobial action by bismuth Tetracycline: Binds to the 30S and possibly 50S ribosomal subunits of susceptbible bacteria to inhibit proteain synthesis Indications Indicated for eradication of H pylori…

  • Metronidazole

    Brands Classes DEA Class; Rx Common Brand Names; Flagyl, Flagyl ER, Flagyl IV RTU Nitroimidazoles metronidazole topical (Rx) Brand and Other Names: MetroCream, MetroGel, MetroLotion, Noritate Classes: Antibacterials, Topical metronidazole vaginal (Rx) Brand and Other Names: MetroGel Vaginal, Vandazole, Nuvessa Classes: Antibiotics, Other;  Vaginal Preparations, Other Description Oral/parenteral/topical/vaginal synthetic nitroimidazole; antibacterial and antiprotozoalUsed for anaerobic bacterial infections and protozoal infections such as…

  • Bismuth Subsalicylate

    Brands Classes DEA Class; OTC Common Brand Names; Kaopectate, Pepto Bismol, Maalox Total Relief, Kaopectate Extra Strength, Pepto-Bismol Maximum Strength Antidiarrheals;  H pylori Agents Description Antimicrobial anti-inflammatory action (bismuth); antisecretory effect (salicylate) Indications Indicated for Diarrhea, Gas, Upset Stomach, Indigestion, Heartburn, Nausea, Traveler’s Diarrhea, Helicobacter Pylori Contraindications Hypersensitivity to bismuth, aspirin, other salicylates Infectious diarrhea, high…

  • Roflumilast

    Brands Classes DEA Class; Rx Common Brand Names; Daliresp, Zoryve Phosphodiesterase-4 Enzyme Inhibitors Description Phosphodiesterase-4 (PDE4) inhibitor that reduces inflammation via an intracellular actionUsed orally to reduce COPD exacerbations in adults with severe COPD, chronic bronchitis, and history of COPD exacerbations; topically to treat plaque psoriasis, including intertriginous areas, in adults and children 12 years…

  • Reslizumab

    Brands Classes DEA Class; Rx Common Brand Names; Cinqair Interleukin Inhibitors;  Monoclonal Antibodies, Anti-asthmatics Description An intravenously administered humanized monoclonal antibody that targets interleukin 5 and reduces eosinophil-meditated inflammation of the airwaysIndicated in adults for add-on maintenance treatment of severe asthma with an eosinophilic phenotypeAnaphylaxis has been reported as early as the second dose; monitor…

  • Omalizumab

    Brands Classes DEA Class; Rx Common Brand Names; Xolair Monoclonal Antibodies, Anti-asthmatics Description Monoclonal antibody directed against IgE given by subcutaneous injectionUsed for moderate to severe allergic asthma in adult and pediatric patients 6 years and older, refractory chronic idiopathic urticaria in those 12 years and older, and for nasal polyps in adults with an…