Category: Drugs Generic
-
Ondansetron
Brands Classes DEA Class; Rx Common Brand Names; Zofran, Zofran ODT, Zuplenz Antiemetics, Selective 5-HT3 Antagonist Description Antiemetic; 5-HT3 receptor antagonistUsed for prevention and treatment of nausea and vomiting due to chemotherapy, radiation therapy and surgeryRisk of dose-dependent QT prolongation and torsades de pointes Indications Indicated for chemotherapy-induced nausea/vomiting prophylaxis (CINV prophylaxis) and radiation-induced nausea/vomiting prophylaxis…
-
Granisetron
Brands Classes DEA Class; Rx Common Brand Names; Sustol, Sancuso, Granisol Oral Solution Antiemetics, Selective 5-HT3 Antagonist Description Oral/intravenous/subcutaneous/transdermal 5-HT3 antagonistUsed to offset nausea/vomiting from moderately or highly emetogenic chemotherapy; also used for prevention of radiation-induced nausea/vomiting, and the immediate-release IV formulation is also approved for postoperative nausea/vomitingRisk of dose-dependent QT prolongation and torsades de pointes…
-
Dolasetron
Brands Classes DEA Class; Rx Common Brand Names; Anzemet Antiemetics, Selective 5-HT3 Antagonist Description Oral/intravenous antiemetic; 5-HT3 receptor antagonistOral tablet used for prevention of chemotherapy-induced nausea/vomiting; injection used for prevention and treatment of PONVRisk of dose-dependent QT prolongation and torsades de pointes Indications Indicated for the treatment of Cancer Chemotherapy Induced Nausea & Vomiting Indicated…
-
Sucralfate
Brands Classes DEA Class; OTC Common Brand Names; Carafate Gastrointestinal Agents, Other Description Oral aluminum-containing sucrose sulfate complex; forms adherent, protective barrier at sites of damaged GI mucosa, shields mucosa from pepsin, acid, and bile; used for esophagitis, GERD, GI ulceration, and stomatitis. Indications Indicated for the treatment of duodenal ulcer not related to NSAID…
-
Citric Acid/Sodium Bicarbonate
Brands Classes DEA Class; OTC Common Brand Names; Alka-Seltzer Heartburn Relief Antacids, Combos Description Citric acid: Antacid; forms sodium citrate which neutralizes stomach acid Sodium bicarbonate: Antacid; reacts with and neutralizes hydrochloric acid in the stomach Indications Indicated for Indigestion/Heartburn Contraindications — Adverse Effects — Warnings Sodium-restricted diet; 575 mg sodium/tablet Phenylketonurics; contains phenylalanine 5.6…
-
Sodium Bicarbonate (Antidote)
Brands Classes DEA Class; Rx Common Brand Names; Antidotes, Other Description Increases blood and urinary pH by releasing a bicarbonate ion, which in turn neutralizes hydrogen ion concentrations 1g of sodium bicarbonate is equivalent to 11.9 mEq each of sodium and bicarbonate Indications Indicated for Cocaine Toxicity Cyanide Toxicity Salicylate Toxicity Barbiturate Toxicity Cardiac Arrest…
-
Sodium Bicarbonate
Brands Classes DEA Class; OTC Common Brand Names; Alkalinizing Agents Description Bicarbonate reacts with H+ ions to form water & carbon dioxide. It acts as a buffer against acidosis by raising blood pH Indications Indicated for Cardiac Arrest Hyperkalemia Metabolic Acidosis Contraindications Hypersensitivity Injection Chloride loss due to vomiting or from continuous gastrointestinal suction Currently…
-
Aluminum Hydroxide/Magnesium Carbonate
Brands Classes DEA Class; OTC Common Brand Names; Gaviscon Extra Strength Liquid, Gaviscon Extra Strength Tablets, Gaviscon Regular Strength Liquid Antacids, Combos Description Neutralizes gastric acid, increases gastric pH Indications Indicated for Gastric Hyperacidity, Heartburn Contraindications Hypersensitivity Adverse Effects Aluminum Chalky taste Constipation Fecal impaction Stomach cramps Nausea Vomiting Aluminum intoxication Hypophosphatemia Osteomalacia Magnesium Diarrhea Hypermagnesemia…
-
Aluminum Hydroxide/Magnesium Trisilicate
Brands Classes DEA Class; OTC Common Brand Names; Gaviscon Regular Strength Tablets Antacids, Combos Description Neutralizes gastric acid, increases gastric pH Indications Indicated for Gastric Hyperacidity, Heartburn Contraindications Hypersensitivity Adverse Effects Aluminum hydroxide Chalky taste Constipation Fecal impaction Stomach cramps Nausea Vomiting Aluminum intoxication Hypomagnesemia Hypophosphatemia Osteomalacia Magnesium Trisilicate Diarrhea Hypermagnesemia Nausea Vomiting Headache Dizziness…
-
Aluminum Hydroxide/Magnesium Hydroxide
Brands Classes DEA Class; OTC Common Brand Names; Maalox Antacids, Combos Description Neutralizes gastric acid, increases gastric pH Indications Indicated for Gastric Hyperacidity, Heartburn Contraindications Hypersensitivity to any component Adverse Effects Aluminum oxide Chalky taste Constipation Fecal impaction Stomach cramps Nausea Vomiting Aluminum intoxication Hypophosphatemia Osteomalacia Magnesium oxide Diarrhea Hypermagnesemia Warnings Prolonged antacid therapy may…
-
Aluminum Hydroxide/Magnesium Hydroxide/Simethicone
Brands Classes DEA Class; OTC Common Brand Names; Mylanta, Mygel, DiGel, Gelusil, Rulox Antacids, Combos Description Aluminum hydroxide: Neutralizes stomach hydrochloride to form AlCl3 salt plus water; increases gastric pH Magnesium hydroxide: Promotes bowel evacuation by causing osmotic retention of fluid, which causes the colon to distend with increased peristaltic activity; forms magnesium chloride when reacts…
-
Aluminum Hydroxide
Brands Classes DEA Class; OTC Common Brand Names; AlternaGEL, Amphojel, Nephrox Antacids Description Antacid; some use for hyperphosphatemia; there is concern regarding Al++ toxicity with long-term use as a phosphate ‘binder’, thus use is limited to patients with high serum phosphate (7mg/dL). Not a primary treatment for PUD. Indications Indicated for use as an antacid to…
-
Dicyclomine
Brands Classes DEA Class; Rx Common Brand Names; Bentyl Anticholinergic Agents Description Parenteral and oral antimuscarinic and anticholinergic agentUsed for diarrhea-predominant irritable bowel syndromeBoxed warning: do not use in infants less than 6 months of age due to severe side effects Indications Indicated for the treatment of irritable bowel syndrome and other functional disturbances of…
-
Rabeprazole
Brands Classes DEA Class; Rx Common Brand Names; Aciphex, Aciphex Sprinkle Proton Pump Inhibitors Description Proton pump inhibitor (PPI); gastric antisecretory agentUsed for GERD, peptic ulcer disease, in combination with antibiotics for the eradication of H. pylori, and for hypersecretory conditions such as ZE syndromeMay have less potential for drug interactions compared to other PPIs…
-
Pantoprazole
Brands Classes DEA Class; Rx Common Brand Names; Protonix Proton Pump Inhibitors Description Oral and IV gastric proton-pump inhibitor (PPI)Used for erosive esophagitis, GERD, Zollinger-Ellison syndrome, duodenal and gastric ulcers, H. pylori eradication with antibiotics, and stress ulcer prophylaxisLowest propensity of PPIs for CYP-based drug interactions Indications Indicated for the treatment of Erosive Esophagitis Associated…