Category: Drugs Generic

  • Senna/Psyllium

    Brands Classes DEA Class; OTC Common Brand Names; Senna Prompt Laxatives, Stimulant Description Senna: Intestinal irritant/stimulant Psyllium: Bulk-producing laxative Indications Indicated for treatment of Constipation Contraindications Hypersensitivity GI obstruction or perforation Ulcerative colitis Symptoms of appendicitis or acute surgical abdomen Fecal impaction GI bleeding Rectal bleeding Adverse Effects Electrolyte imbalance Potassium loss Abdominal cramping Excessive…

  • Senna

    Brands Classes DEA Class; OTC Common Brand Names; Senokot, ExLax Regular Strength, Lax Pills, Little Tummys Stimulant Laxative Drops, Senexon, SennaGen, Senna Smooth, ExLax Maximum Strength, SenokotXTRA Laxatives, Stimulant Description Intestinal irritant and stimulant Indications Indicated for treatment of Constipation Contraindications Hypersensitivity GI obstruction or perforation Ulcerative colitis Symptoms of appendicitis or acute surgical abdomen Acute…

  • Castor Oil/Trypsin

    Brands Classes DEA Class; OTC Common Brand Names; Granulex, Xenaderm, Optase Protectants, Topical Description Prescription only topicals used in wound care; stimulates local circulation, reduce pain/odor, debride necrotic tissue, improve epithelization, and acts as barrier; approved for sunburn, varicose ulcers, dehiscent wounds, decubital ulcers, and debriding of eschar. Indications Indicated for treatment of Treatment of Skin…

  • Castor Oil

    Brands Classes DEA Class; OTC Common Brand Names; Fleet Castor Oil, Emulsoil Laxatives, Other Description Irritant/stimulant laxative Indications Indicated for treatment of Constipation Colonic Evacuation Contraindications Hypersensitivity, GI obstruction or perforation, severe impaction, symptoms of appendicitis or acute surgical abdomen, ulcerative colitis, rectal fissures Adverse Effects Dizziness Abdominal cramps Diarrhea Nausea Electrolyte disturbance Hypotension Pelvic…

  • Bisacodyl

    Brands Classes DEA Class; OTC Common Brand Names; Dulcolax, Correctol, BisacEvac, Bisacolax, Codulax, Alophen, Feen A Mint, Fleet Stimulant Laxative, Laxit, Modane, Dulcolax for Women, Fleet Bisacodyl Enema, Fleet Bisacodyl Suppository  Laxatives, Stimulant Description Stimulant laxative often used to prepare patients for radiological GI procedures; administered orally or rectally; reclassified in 1996 as a Category III…

  • Methylcellulose

    Brands Classes DEA Class; OTC Common Brand Names; Citrucel  Laxatives, Bulk-Producing Description Bulk producing laxative Indications Indicated for Constipation Contraindications Hypersensitivity, bowel obstruction, symptoms of appendicitis or acute surgical abdomen, GI ulceration/adhesions, fecal impaction, dysphagia, rectal bleeding Adverse Effects Flatulence Impaction Excessive bowel activity Warnings Without taking adequate fluid the product may swell and block…

  • Loperamide/Simethicone

    Brands Classes DEA Class; OTC Common Brand Names; Imodium Multi-Symptom Relief Antidiarrheals Description Antidiarrheal and antiflatulent combination productApproved for self-treatment of acute diarrhea accompanied by bloating, cramps, and gasSupratherapeutic doses of loperamide have been associated with serious, sometimes fatal, cardiac events Indications Indicated for self-treatment of acute diarrhea accompanied by bloating, cramps, pressure or flatulence.…

  • Loperamide

    Brands Classes DEA Class; OTC Common Brand Names; Imodium, K-Pek II, NeoDiaral, Diaraid Antidiarrheals Description Oral antidiarrheal agent related to opiates; actions more targeted to periphery; decreases peristalsisUsed primarily for acute, nonspecific diarrhea, including nonspecific traveler’s diarrheaDue to serious and sometimes fatal cardiac events and respiratory depression, contraindicated in pediatric patients less than 2 years; recommended…

  • Rolapitant

    Brands Classes DEA Class; Rx Common Brand Names; Varubi Antiemetic Agents;  NK1 Receptor Antagonists Description Substance P/neurokinin 1 (NK1) receptor antagonistUsed in combination with dexamethasone and a 5-HT3 receptor antagonist for the prevention of CINVContraindicated with CYP2D6 substrates with a narrow therapeutic index, such as thioridazine and pimozide Indications Indicated for delayed chemotherapy-induced nausea/vomiting prophylaxis,…

  • Fosaprepitant

    Brands Classes DEA Class; Rx Common Brand Names; Emend IV NK1 Receptor Antagonists;  Antiemetic Agents Description Selective substance P (NK1) antagonist, fosaprepitant is prodrug of aprepitantUsed for prevention of chemotherapy-induced nausea/vomiting (CINV) due to highly and moderately emetogenic regimens; IV aprepitant (Aponvie) used for prevention of post-operative nausea/voming (PONV)For CINV use with in combination with…

  • Aprepitant

    Brands Classes DEA Class; Rx Common Brand Names; Cinvanti, Aponvie, Emend PO Antiemetic Agents;  NK1 Receptor Antagonists Description Selective substance P (NK1) antagonist, fosaprepitant is prodrug of aprepitantUsed for prevention of chemotherapy-induced nausea/vomiting (CINV) due to highly and moderately emetogenic regimens; IV aprepitant (Aponvie) used for prevention of post-operative nausea/voming (PONV)For CINV use with in combination…

  • Droperidol

    Brands Classes DEA Class; Rx Common Brand Names; Inapsine Antiemetic Agents;  Description Parenteral butyrophenone derivative, sedative-hypnotic structurally similar to haloperidol; more potent antiemetic, but less antipsychotic properties compared to haloperidol; due to the risk of QT prolongation and torsade de pointes, limited indication for surgical nausea and vomiting prophylaxis in patients refractory to other treatments.…

  • Metoclopramide

    Brands Classes DEA Class; Rx Common Brand Names; Reglan, Metozolv ODT Antiemetic Agents;  Prokinetic Agents Description Oral, parenteral, and nasal GI prokinetic agentUsed for diabetic gastroparesis and select adults with GERD; injection helpful for PONV prevention, chemotherapy-induced emesis, and as a procedural adjunctUse should be kept to 12 weeks or less due to risk for…

  • Netupitant/Palonosetron

    Brands Classes DEA Class; Rx Common Brand Names; Akynzeo, fosnetupitant Antiemetic Agents;  Antiemetics, Selective 5-HT3 Antagonist;  NK1 Receptor Antagonists Description Combination of a selective substance P neurokinin 1 (NK1) receptor antagonist and highly selective 5-HT3 receptor antagonistUsed with dexamethasone for prevention of CINV due to chemotherapy, including, but not limited to, highly emetogenic chemotherapyPalonosetron prevents…

  • Palonosetron

    Brands Classes DEA Class; Rx Common Brand Names; Aloxi Antiemetics, Selective 5-HT3 Antagonist Description Parenteral 5-HT3 receptor antagonistUsed for prevention of post-operative nausea and vomiting and acute and delayed chemotherapy-induced nausea and vomitingLong half-life allows for one-time dosing within a 7-day period for CINV Indications Indicated for prevention of acute N/V associated with moderately or…