Classes
DEA Class; Rx
Common Brand Names; BACiiM, Baciguent, Bacitracin Ophthalmic Ointment
- Antibiotics, Other
Description
Ophthalmic, parenteral, and topical polypeptide antibiotic
Used for superficial ocular infections involving the conjunctiva and/or cornea, infants with pneumonia and empyema due to susceptible staphylococci, and infection prevention in minor cuts, scrapes, or burns
Active mainly against gram-positive bacteria
Indications
Indicated for the prevention of skin and skin structure infections after a minor compromise in skin integrity such as minor burns or skin abrasion.
Contraindications
Hypersensitivity
Adverse Effects
- Nephrotoxic reactions including albuminuria, cylindruria, and azotemia
- Nausea and vomiting
- Itching
- Nausea/vomiting
- Blood dyscrasias
- Diaphoresis
- Pain at injection site
- Rash
- Itching
- Pain
- Hypersensitivity reaction (rare)
Warnings
Do not administer IV; severe thrombophlebitis could occur
Prescribing in absence of proven or strongly suspected bacterial infection or prophylactic indication may not benefit patient and increases development of bacterial resistance
Maintain adequate fluid intake
Antibiotics may cause overgrowth of nonsusceptible organisms, including fungi
Pregnancy and Lactation
Pregnancy Category: C
Lactation: Unknown whether distributed in breast milk
Maximum Dosage
IM not recommended; however, 100,000 units/day IM (not to exceed 25,000 units/dose IM) has been used for the treatment of pneumonia.
IM not recommended; however, 100,000 units/day IM (not to exceed 25,000 units/dose IM) has been used for the treatment of pneumonia.
IM not recommended; specific dosing for adolescents not available(use Children dosing – 1200 units/kg/day IM has been used for the treatment of pneumonia.)
IM not recommended; however, 1200 units/kg/day IM has been used for the treatment of pneumonia.
> 2.5 kg: 1000 units/kg/day IM.
<= 2.5 kg: 900 units/kg/day IM.
How supplied
Bacitracin
ointment
- 500unit/g
ointment
- 500 unit/g (3.5 g)