Paracetamol/Caffeine/Pyrilamine

DEA Class;  OTC

Common Brand Names; Midol Complete

Analgesics, Other combo

Hypersensitivity to drug or components

Risk of hepatotoxicity; risk is higher in alcoholics or with use of more than one acetaminophen-containing product

Caution regarding daily acetaminophen consumption; do not exceed 3-4 g/day and do not take for prolonged duration G6PD deficiency

May cause CNS depression, which may impair mental and physical abilities; caution patients about performing tasks requiring mental alertness, including operating heavy machinery

Caution with glaucoma, difficulty in urination caused by prostate gland enlargement, and emphysema or chronic bronchitis

Allergic reactions reported with acetaminophen; discontinue immediately if symptoms of allergic or hypersensitivity reactions occur

Additive sedation may occur if used with alcohol or sedative drugs

Acetaminophen associated with increased risk for rare, but serious skin reactions that can be fatal; these reactions include Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP); symptoms may include skin redness, blisters, and rash

Pregnancy category: C

Lactation: Excreted in breast milk

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

acetaminophen/caffeine/pyrilamine

caplet

• 500mg/60mg/15mg