Aluminum Hydroxide/Magnesium Hydroxide

Prolonged antacid therapy may result in hypophosphatemia; aluminum in antacid may form insoluble phosphate complexes, which may result in decreased phosphate absorption in the GI tract; severe hypophosphatemia may lead to anorexia, malaise, muscle weakness, and osteomalacia

Prolonged therapy may result in aluminum intoxication or hypermagnesemia, particularly in renal impairment; aluminum intoxication may result in osteomalacia or dialysis encephalopathy

If used for self-medication, instruct patient to consult their physician before initiating if they are on a magnesium and/or sodium-restricted diet; not to be administered for longer than 14 days

May increase or decrease rate &/or degree of absorption of concomitantly administered oral drugs by changing GI transit time or by binding the drug