Neomycin/Polymyxin B/Hydrocortisone/Bacitracin

DEA Class; Rx

Common Brand Names; Neo-Polycin HC

Indicated for the treatment of corticosteroid-responsive inflammatory ocular conditions where a bacterial ophthalmic infection or a risk of bacterial ophthalmic infection exists (e.g., inflammation of palpebral and bulbar conjunctiva, cornea and anterior segment of the globe where the inherent risk of corticosteroid use in bacterial conjunctivitis is accepted to obtain a decrease in edema and inflammation; also in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns, or penetration of foreign objects).

Hypersensivity to neomycin

Glaucoma

Viral diseases of cornea and conjunctiva (epithelial herpes simplex keratitis, vaccinia, varicella)

Mycobacterial infection of eye & fungal diseases of ocular structures

Hypersensitivity

• Allergies
• Glaucoma
• Rash
• Superinfection (herpes)
• Skin sensitization
• Burning
• Itching
• Irritation
• Dryness
• Folliculitis
• Hypertrichosis
• Acneiform eruptions
• Hypopigmentation
• Perioral dermatitis
• Allergic contact dermatitis
• Maceration of the skin
• Secondary infection
• Skin atrophy
• Striae
• Miliaria

Not used much, because of hypersensitivity reactions to neomycin; also, because of steroid component, adequate follow up is essential

Prolonged use or misuse of ocular corticosteroid may result in glaucoma, superinfection (herpes) etc

Newer agents have better steroid & antibiotic coverage

For external use only

Pregnancy Category: C

Lacation: Unknown