Classes
DEA Class; OTC
Common Brand Names; Mag-G, Magonate, Magtrate
- Electrolytes
Description
Cofactor for many enzymatic pathways involved in phosphate transfer reactions that use ATP and other nucleotides as substrates (eg, oxidative phosphorylation, oxygen radical reduction)
Indications
Indicated as a Dietary Supplement
Contraindications
Hypersensitivity
Hypermagnesemia
Adverse Effects
Diarrhea
Warnings
Use caution in severe renal impairment
Use extreme caution in patients with myasthenia gravis or other neuromuscular diseases
May use for the treatment of constipation occasionally; prolonged use may result in serious side effects
Patient should inform physician about prescription nonprescription medications being taken, especially other products with magnesium or tetracycline
Inform physician about having or ever having kidney disease, intestinal disease, or stomach problems
If pregnant or planning to become pregnant or breastfeeding, discuss these with physician
Pregnancy and Lactation
Pregnancy Category: A; elemental magnesium dietary reference intake during pregnancy is 350-400 mg/day for adult women
Lactation: Distributed in breast milk, elemental magnesium dietary reference intake for breast feeding women is 310-360 mg/day for adult women
Maximum Dosage
RDA (Elemental Magnesium)
Males: 400-420 mg PO qDay
18-30 (Females)
- 310 mg PO qDay
- Pregnancy: 350 mg PO qDay
- Lactation: 310 mg PO qDay
>30 years (Females)
- 320mg/day
- Pregnant women: 360 mg/day
- Lactating women: 320 mg/day
Supplement
Liquid: 5-10 mL initially (first day)
Tablet: 2-4 tab initially (first day)
Titrate to higher dose until stool softens and remains soft; reduce intake if loose stool
Pediatric
Magnesium Supplementation
Dietary reference for PO intake of elemental magnesium varies in children according to age
<6 months: 30 mg/day
6-12 months: 75 mg/day
1-3 years: 80 mg/day
3-8 years: 130 mg/day
8-13 years: 240 mg/day
Adolescent boys 13-18 years: 410 mg/day
Adolescent girls (13-18 years)
- 360 mg/day
- Pregnant: 400 mg/day
- Lactating: 360 mg/day
How supplied
Magnesium gluconate