Perampanel

DEA Class;  Rx

Common Brand Names; Fycompa

Known hypersensitivity to oxcarbazepine or any of its components, or to eslicarbazepine acetate

• Dizziness (16-43%)
• Somnolence (9-18%)
• Headache (11-13%)
• Fatigue (8-12%)
• Irritability (4-12%)
• Falls (2-10%)
• Nausea (6-8%)
• Ataxia (1-8%)
• Vertigo (3-5%)
• Balance disorder (3-5%)
• Back pain (2-5%)
• Weight gain (4%)
• Vomiting (2-4%)
• Anxiety (3-4%)
• Blurred vision (1-4%)
• Dysarthria (1-4%)
• Cough (1-4%)
• Hypoaesthesia (3%)
• Constipation (2-3%)
• Arthralgia (2-3%)
• Extremity pain (2-3%)
• Aggression (1-3%)
• Anger (1-3%)
• Myalgia (1-3%)
• Diplopia (1-3%)
• Injuries due to falls (1-3%)
• Hypersomnia (1-3%)
• Hyponatremia (2%)
• Contusions (2%)
• Oropharyngeal pain (2%)
• Asthenia (1-2%)
• Confusional state (1-2%)
• Euphoric mood (1-2%)
• Altered mood (1-2%)
• Abnormal coordination (1-2%)
• Musculoskeletal pain (1-2%)
• Peripheral edema (1-2%)
• Memory impairment (1-2%)
• Paraesthesia (1-2%)
• Acute psychosis, hallucinations, delusions, paranoia, delirium, disorientation, drug reaction with eosinophilia and systemic symptoms (DRESS)/multiorgan hypersensitivity

—

There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antiepileptic drugs (AEDs)

Perampanel and/or its metabolites are present in rat milk, and are detected at concentrations higher than that in maternal plasma