Temazepam

DEA Class;  Rx

Common Brand Names; Restoril

Documented hypersensitivity

Acute alcohol intoxication

Narrow-angle glaucoma (questionable)

• Drowsiness (9.1%)
• Dizziness (4.5%)
• Lethargy (4.5%)
• Hangover (2.5%)
• Diarrhea (1.7%)
• Euphoria (1.5%)
• Weakness (1.4%)
• Confusion (1.3%)
• Vertigo (1.2%)
• Amnesia
• Angioedema
• Blood dyscrasias
• Sleep-related behavior (eg, sleep driving, sleep cooking, sleep eating)
• Ataxia

Use caution in COPD, sleep apnea, renal/hepatic disease, impaired gag reflex, open-angle glaucoma (questionable), alcoholism, respiratory disease, depression, suicidal ideation

May impair ability to perform hazardous tasks

Caution with IV use in shock, coma, and depressed respiration and in patients who recently received other respiratory depressants

Anterograde amnesia may occur

Use caution in patients with history of drug abuse or acute alcoholism; tolerance, psychological and physical dependence may occur with prolonged use

Use in myasthenia gravis is allowed in limited circumstances

Use caution in severe respiratory depression and depressed neuroses, psychotic reactions

Paradoxical hyperactive aggressive behavior reported

Therapy can cause drowsiness and a decreased level of consciousness; patients, particularly the elderly, are at higher risk of falls

May cause hyperactive or aggressive behavior

Use of drug, particularly in patients at elevated risk of abuse, necessitates counseling about risks and proper use of drug along with monitoring for signs and symptoms of abuse, misuse, and addiction; do not exceed recommended dosing frequency

Avoid or minimize concomitant use of CNS depressants and other substances associated with abuse, misuse, and addiction (eg, opioid analgesics, stimulants); advise patients on proper disposal of unused drug; if a substance use disorder is suspected, evaluate patient and institute (or refer them for) early treatment, as appropriate

Pregnancy Category: X

Lactation: Avoid if breastfeeding