Aspirin/Citric Acid/Sodium Bicarbonate

DEA Class;  OTC

Common Brand Names; Alka Seltzer Original

Antacid

Aspirin irreversibly blocks the COX pathway; citric acid and sodium bicarbonate neutralize the stomach acid.

Is used for the relief of heartburn, acid indigestion, upset stomach, as well as headache, body aches, and pain alone.

Aspirin may cause stomach bleeding.

Indicated for heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches.

Hypocalcemia, hypochloremia, respiratory alkalosis

Hypersensitivity to aspirin or any component

Immediately before or after heart surgery

Concomitant administration with prescription medication for diabetes, gout, or arthritis

Flatulence

Rebound hyperacidity

Stomach cramps

Vomiting

Children and teenagers who have or are recovering from chickenpox or flu-like symptoms should not use this product; when using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness

Aspirin may cause severe allergic reactions, including facial swelling, shock, asthma (wheezing), or hives

NSAIDs may cause stomach bleeding; risk of bleeding increases with presence of stomach ulcers or bleeding problems, age 60 or older, take higher dose or take for longer time than directed, having 3 or more alcoholic drinks every day while using this product, taking blood thinner or steroid drug

Use caution and ask a healthcare practitioner if history of stomach aches, including heartburn, experiencing high blood pressure, liver cirrhosis, heart disease, or kidney disease, currently taking a diuretic, history of or currently experiencing asthma, on a sodium restriction diet

Pregnancy; Ask a healthcare professional; important not to use aspirin during the last 3 months of pregnancy unless prescribed by a physician; may cause complications in the unborn child or during delivery

Lactation; Ask a healthcare professional

Adults

18 to 59 years: Aspirin 3.5 grams/day PO (Alka-Seltzer or equivalent: Regular Strength 8 tablets/day PO; Extra Strength 7 tablets/day PO)
60 years and older: Aspirin 1.5 grams/day PO (Alka-Seltzer or equivalent: Regular Strength 4 tablets/day PO; Extra Strength 3 tablets/day PO)

Geriatric

Aspirin 1.5 grams/day PO (Alka-Seltzer or equivalent: Regular Strength 4 tablets/day PO; Extra Strength 3 tablets/day PO)

Adolescents

Aspirin 3.5 grams/day PO (Alka-Seltzer or equivalent: Regular Strength 8 tablets/day PO; Extra Strength 7 tablets/day PO)

Children

12 years: Aspirin 3.5 grams/day PO (Alka-Seltzer or equivalent: Regular Strength 8 tablets/day PO; Extra Strength 7 tablets/day PO)
1 to 11 years: Safety and efficacy have not been established.

Infants

Safety and efficacy have not been established.

Neonates

Safety and efficacy have not been established.

Effervescent Tablet

325mg/1000mg/1916mg